T5 and Telomere Science

Telomere Science

Telomere science is helping keep cells is optimal condition.

It may not seem like it, but when you buy a health product, you are purchasing the end result of months, or even years, of research and development. Every ingredient is there for a reason.

The aim with T5 was to find natural products which peer-reviewed articles suggested may have a positive effect on the telomere in healthy cells The telomere is a sort of biological clock. It is attached to the chromosomal DNA and shortens every time healthy cells divide. The shortening telomere eventually reaches the irreversible point of ‘cellular senescence’, after which the cell no longer divides or functions in the same way as a young cell. In particular we sought products which affect activity and levels of telomerase. Often referred to as ‘the fountain of youth’[1], telomerase is an enzyme responsible for transcribing the telomere onto the end of the chromosome and for maintaining the length of it.

After reading a fat stack of literature, including studies which addressed oral absorption, dosages and safety, we settled on Astragalus extract, Baicalin, Glutathione, Selenium and an antioxidant mix as the most effective combination.

Astragalus Extract

Astragulus membranaceous is a fundamental herb of Chinese medicine. It contains two powerful and supremely expensive ‘small molecule selective telomerase activators’ known as Astragaloside IV and Cycloastragenol. The levels of Cycloastragenol in T5 are miniscule, however some Astragaloside IV is converted to it during digestion[2]. In-vitro studies have shown that Astragalus extracts can selectively increase telomerase activity by up to 3.3 times[3], slow telomere loss in immune cells and upregulate the level of telomerase in skin cells through increasing telomerase production[4]. Animal studies have shown increased telomere length and decrease in various signs of aging in old mice[5]. The effect of extracts on cells was cumulative, with five months exposure having a greater effect than 7 days[4]. A human trial showed that after 12 months on a protocol which included Astragalus extract, cells begin to model a more youthful configuration and show fewer short telomeres than those from humans that were not on the protocol[6]. Astragaloside IV and Cycloastragenol equally inhibit oxidative stress[7] (free-radical damage) which affects the telomere more than other parts of the chromosome[8].

Baicalin and Telomere Science

Baicalin is a flavone extracted from the medicinal herb Scutellaria baicalensis. In-vitro, baicalin protects skin cells from the telomere damage usually inflicted by Ultraviolet A radiation[9]An inhibitory effect of baicalin in cells and skin exposed to UVB radiation has also been seen[10,11]. Along with oxidative damage, UV radiation is a major cause of visible skin aging (‘photoaging’). Usefully, baicalin is also an antioxidant. Although most studies have been in-vitro, other studies have shown both that baicalin is absorbed in the colon (that is, not destroyed by digestion[12] and that certain metabolic products of oral ingestion are reproduced when pre-digested baicalin is applied directly to intestinal cells[13]. In other words, there are strong indications that baicalin is effective when taken orally.

Glutathione

Glutathione is synthesised by every human cell and functions as the body’s master antioxidant, mopping up the telomere-damaging free radicals and peroxides that result from environmental exposure to toxins and from normal metabolism.  Telomere length and integrity are strongly related to oxidative stress. Glutathione also helps regenerate other antioxidants, including vitamins C and E and regulates telomerase[14]. Research has shown that the levels of active glutathione in the cell decrease under conditions of oxidative stress, leading to telomere damage[15,16].  Oral glutathione intake has recently been shown to effectively boost cellular glutathione levels in humans[17].

Antioxidants and Selenium

Having already established that oxidative stress is a major factor in telomere damage, we decided to include a broad range antioxidant in T5. Although research is limited, one cross-sectional analysis reported that telomeres were 5.1% longer in women using a mixed antioxidant multi daily and that higher intakes of vitamins C and E from food are associated with telomere length[18]. Selenium, cellular levels of which decrease with age, is a potent antioxidant that has been shown to increase telomerase activity and genetic expression of its sub-unit hTERT in rat and human liver cells[19,20].

What Else?

Of course, not everything can go into a supplement! During the research process we also discovered that moderate exercise and a diet high in fruits and vegetables are telomere protective, while smoking and alcohol consumption are telomere unfriendly. Ultimately it comes down to looking after your telomeres, so that they can look after you.

Author Bio:

Sara Lake
Sara Lake is a Christchurch (New Zealand) based nutritionist, food blogger and MSc student of human nutrition at Massey University.

References:

1.            University of Copenhagen. ‘Fountain of youth’ telomerase: Scientists successfully map enzyme that has rejuvenating effect on cells. 2013.

2.            Zhou, R.N., et al., Pharmacokinetic evidence on the contribution of intestinal bacterial conversion to beneficial effects of astragaloside IV, a marker compound of astragali radix, in traditional oral use of the herb. Drug metabolism and pharmacokinetics, 2012. 27(6): p. 586-97.

3.            Molgora, B., Bateman, R., Sweeney, G., Finger, D., Dimler, T., Effros, R., Vlenzuela, H., Functional Assessment of Pharmacological Telomerase Activators in Human T Cells. Cells, 2013. 2: p. 57-66.

4.            Fauce, S.R., et al., Telomerase-Based Pharmacologic Enhancement of Antiviral Function of Human CD8(+) T Lymphocytes. Journal of Immunology, 2008. 181(10): p. 7400-7406.

5.            Bernardes de Jesus, B., et al., The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence. Aging cell, 2011. 10(4): p. 604-21.

6.            Harley, C., Liu, W., Blasco, M, Vera, E., Andrews, WH., Briggs, LA., Raffaele, JM., A natural product telomerase activator as part of a health maintenance program. Rejuvenation Research, 2011. 14(1): p. 45-56.

7.            Zhao, Y., et al., Astragaloside IV and cycloastragenol are equally effective in inhibition of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in the endothelium. Journal of ethnopharmacology, 2015. 169: p. 210-8.

8.            von Zglinicki, T., Oxidative stress shortens telomeres. Trends in biochemical sciences, 2002. 27(7): p. 339-44.

9.            Min, W., et al., Effects of baicalin on ultraviolet A-induced telomere damage in cultured human primary fibroblasts. Zhonghua Pifuke Zazhi, 2011. 44(9): p. 639-642.

10.         Min, W., et al., Inhibitory effects of Baicalin on ultraviolet B-induced photo-damage in keratinocyte cell line. The American journal of Chinese medicine, 2008. 36(4): p. 745-60.

11.         Bing-Rong, Z., et al., Protective effect of the Baicalin against DNA damage induced by ultraviolet B irradiation to mouse epidermis. Photodermatology, photoimmunology & photomedicine, 2008. 24(4): p. 175-82.

12.         Li, L.J., J. Li, and H.W. Lou, [Study on in situ intestinal absorption of baicalin contained in Tiangou Jiangya capsules]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013. 38(6): p. 894-8.

13.         Morisaki, T., et al., Baicalin pharmacokinetic profile of absorption process using novel in-vitro model: cytochrome P450 3A4-induced Caco-2 cell monolayers combined with rat intestinal rinse fluids. Journal of Pharmacy and Pharmacology, 2013. 65(10): p. 1526-1535.

14.         Pallardo, F.V., et al., Role of nuclear glutathione as a key regulator of cell proliferation. Molecular aspects of medicine, 2009. 30(1-2): p. 77-85.

15.         Kurz, D.J., et al., Chronic oxidative stress compromises telomere integrity and accelerates the onset of senescence in human endothelial cells. Journal of cell science, 2004. 117(Pt 11): p. 2417-26.

16.         Richter, T. and T. von Zglinicki, A continuous correlation between oxidative stress and telomere shortening in fibroblasts. Experimental gerontology, 2007. 42(11): p. 1039-1042.

17.         Richie, J.P., Jr., et al., Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. European journal of nutrition, 2015. 54(2): p. 251-63.

18.         Xu, Q., et al., Multivitamin use and telomere length in women. American Journal of Clinical Nutrition, 2009. 89(6): p. 1857-1863.

19.         Yu, R.A., et al., Telomerase activity and telomerase reverse transcriptase expression induced by selenium in rat hepatocytes. Biomedical and environmental sciences : BES, 2009. 22(4): p. 311-7.

20.         Liu, Q., et al., Effects of trace elements on the telomere lengths of hepatocytes L-02 and hepatoma cells SMMC-7721. Biological trace element research, 2004. 100(3): p. 215-27.

How to treat arthritis correctly

Arthritis Treatment

For arthritis support to be effective, you should treat the cause not the pain.

Arthritic pain is a very serious problem for many people. Anyone who is dealing with arthritis knows that it is a difficult condition to manage. Pain can be excruciating, and everyday tasks become complicated. Impairment in the ability to perform simple daily tasks can severely impact your work or the care you can provide for your family.

What causes arthritis?

A number of things. Injury or other damage to the joints, occupation (constant lifting and bending and carrying heavy loads), obesity, inheritance, or simple wear and tear. In fact, arthritis is often associated with aging, but arthritic pain does not have to be endured as part of the aging process. It is possible to live a normal life without restrictions – provided you treat the condition correctly.

Think about it for a moment. Arthritis is characterized by pain, aching, stiffness, inflammation and swelling in and around the joints. Simply walking, getting up out of a chair, or opening a jar may cause discomfort. The source of the pain is often attributed to the damage or deterioration of the joint cartilage, most specifically in degenerative arthritis. That’s important to note, because rebuilding or repairing cartilage is crucial to preventing and dealing with arthritis.

In a normal, healthy body cartilage covers the joints and protects the bones from rubbing together. For healthy cartilage we need lots of collagen. In fact, collagen it is the building block for all our body’s major systems. It is truly the glue that holds the body together.

Unfortunately, as we get older, the body’s natural ability to make collagen slows down, and that’s what’s needed to maintain and rebuild cartilage tissue. If we don’t have enough collagen, the cartilage between our joints begins to deteriorate and it gradually loses its protective cushioning. That’s when we begin to see the results of degenerative arthritis.

But it’s not all bad news. Arthritis support is available. You can begin to repair and rebuild the damaged cartilage – thereby reducing your pain and increasing mobility – simply by replenishing your collagen levels. While conventional treatment centres around reducing inflammation and swelling, if you don’t rebuild your cartilage, you will simply be treating the pain and not the cause.

Effective arthritis support such as collagen supplements target the problem and lead to a better quality of life. Be pro-active in your arthritis treatment. Treat the problem, not the symptoms.

Sensitive skin – what can I do?

Sensitive Skin

Sensitive skin problems can affect all aspects of your life.

Our skin has a very important function. It acts as a barrier, keeping bacteria, viruses, fungi, germs and harmful chemicals from getting into our bodies. It protects us from cold, heat and sun, as well as other environmental factors. Our skin plays a crucial role in our wellbeing, but for some people skin sensitivity can be a problem. In various studies, as much as 50% of women and 40% of men have reported having sensitive skin.

What does sensitive skin mean?

‘Sensitive skin’ is the lay term used for people who easily break out in rashes or bumps or who are prone to dryness, itchiness and redness. Those with sensitive skins may react to excessive use of makeup, chemicals in skincare products, or sunlight, with the result of stinging, burning, itching and/or peeling. The degree of sensitivity varies from person to person, but for people with sensitive skins, a skin reaction can flare up at any time. That can result in further skin irritation because the skin barrier has been disturbed.

Those with easily irritated skin should play it safe with their face. Use mild products or those especially designed for sensitive skin, and avoid microdermabrasion treatments, which strip the skin of its protective barrier.

Retaining and regulating moisture is essential. Dry skin from any cause is irritable and sensitive. While the tendency is to compensate by applying all sorts of topical creams, these may only result in further irritation. This is where collagen supplements are a great choice for replenishing skin moisture and restoring healthy skin. They moisturize and rejuvenate from within, so the skin’s integrity is not impaired.

5 steps to take for sensitive skin
  • Avoid excessive exposure to skin-damaging environmental factors such as sun, wind or excessive heat or cold.
  • Wear a sunscreen year round.
  • Use mild products or those especially designed for sensitive skin.
  • Avoid antibacterial ingredients.
  • Minimize sky dryness, but don’t overuse harsh topical creams. A collagen supplement is ideal as it works from the inside out to restore collagen and thus the skin’s moisture levels.

Affordable and effective healthy skin treatment

Healthy Skin Treatment

A good skin treatment can help fight aging, but the trick is knowing which skincare product is the right choice.

Wrinkles and fine lines are two of the most common skin-aging indicators.  They occur when the elastin and collagen in our body’s tissues begin to degrade and cause the skin to lose its firmness.  Exposure to sun, smoke, pollution and an unhealthy lifestyle can all lead to collagen degradation – and consequently premature aging and unhealthy skin.

Good skin treatment

Along with proper nutrition and exercise, a good skin treatment can help fight aging – but the trick is knowing which skincare product is the right choice.  Despite the thousands of products that claim to address skin problems, not all are made with ingredients that are backed by science.

Three proven ingredients that promote healthy skin and help to turn back the clock are Matrixyl, Argireline and hyaluronic acid (HLA).

Matrixyl works by stimulating the skin to synthesize more collagen as well as other proteins, such as elastin and glycosaminoglycans (GAGs) – all important compounds for the support of healthy skin.  It’s able to penetrate the skin to reach the fibroblast cells and incite those cells to synthesize collagen.  This is important, because while some cosmetic manufacturers claim to be applying collagen to the skin, in fact the collagen molecule is too large to penetrate the skin’s outer layer – it must be produced by the skin itself from the inside.

Argireline works on muscle nerve endings, releasing neurotransmitters, which help reduce muscle contraction thereby preventing the formation of lines and wrinkles.  It’s been likened to Botox in the way it relaxes facial muscles, though it’s less invasive, less expensive and non-toxic.

Skin topography analyses have proven argireline to reduce the depth of wrinkles by 27% to 60% when applied via a topical cream such as Puraz COMPLETE.

Hyaluronic acid is a major contributor to youthful skin.  It works by attracting and binding water beneath the skin surface, absorbing up to 1000 times its weight in moisture.  Because of this intensive hydration, it visibly gives fullness to the face, reducing fine lines and wrinkles and smoothing the surface of the skin with a plumping action.  It is also a ‘scavenger’ of free radicals, helping to remove the oxidants caused by ultraviolet rays.

Skin Treatment with Puraz COMPLETE

Puraz COMPLETE contains all three ingredients to help fight aging and restore your skin to health.  It’s the first time a high-end skin cream and serum using the most advanced technology is available to the market at less than a third of the normal price, but with higher concentration of the key active ingredients.  When applied daily it can help reduce the depth of wrinkles, especially in the forehead and around the eyes, make the skin smoother, produce lasting moisturizing of the skin, and help you look and feel younger.  In fact, Puraz COMPLETE anti-aging day serum and Puraz COMPLETE anti-aging night cream is scientifically proven to increase Type 1 collagen synthesis in skin cells by up to 93.1% (Independent in vitro studies,Trinity Bioactives 2011) – which leads to healthy, youthful skin.

Buy Puraz COMPLETE

Fish oil supplements by Puraz

Fish Oil Supplements

Our bodies cannot produce their own omega-3 fatty acids, so they must be consumed from our diet or from supplements such as krill oil.

We all know that high-quality fish oil supplements are good for us, right?

Well, studies show that krill oil is even better.

Like regular fish oil, krill oil contains high levels of the omega-3 fatty acids DHA (Docosahexaenoic acid) and EPA (Eicosapentaenoic acid). Omega-3 fats are essential for our health, especially our cardiovascular health and mental health.  They are also vital for metabolism and our central nervous system, basic functions like building cell membranes, and alleviating inflammatory diseases.

But our body cannot produce its own omega-3 fatty acids, so they must be consumed from our diet or from supplements. It can, however, be difficult to get the required levels of fresh oily fish in our daily diet, so supplements like fish oil and krill oil are ideal.

But what sets krill oil apart from regular fish oil is that the fatty acids in krill oil are far better absorbed by the body.

The omega-3 fatty acids contained in fish oil are found in a triglyceride form. Those in krill oil are found in a phospholipid form. Because the fats in human cell walls are also of a phospholipid structure, the absorption rate of omega-3s in krill oil dramatically increases.

But that’s not the only benefit. Krill oil contains a natural antioxidant called astaxanthin, which regular fish oils don’t have.

Antioxidants, of course, neutralise free radicals, which are harmful metabolic byproducts that damage cells and tissues throughout our body. If the antioxidants in our bodies are depleted, or if free radical production becomes excessive, damage occurs. That’s why the astaxanthin in krill oil is highly beneficial.

But there’s another reason why this potent antioxidant is so important. You don’t get this in regular fish oil. And that means without it, fish oils can be susceptible to rancidity.

We’ve seen that highlighted lately in the news. A recent study found that many retail fish oil supplements were of poor quality, containing high levels of oxidation by-products, which indicate rancidity, and less Omega 3 than stated on the label.  That could mean that the fish oil you are taking may actually be rancid, which can do more damage to your body than good.

The study didn’t include krill oils, but Puraz had their krill oil product independently tested to put consumers’ minds at rest. Puraz Krill Oil was shown to exceed its stated quantities of Omega-3, EPA and DHA with zero rancidity.

Puraz Krill Oil’s high antioxidant value means it won’t oxidise and go rancid, like some fish oils can. It’s also free from heavy metals and mercury. And one more benefit to krill oil – it doesn’t repeat on you like fish oils do.

Can it get any better than that?

Dealing with knee pain and the healing process

Knee pain

Knee pain can be debilitating, but a high-quality supplement and healthy living can get your life back on track.

Knee pain is a common complaint, with symptoms often sneaking up gradually. Your range of motion may slowly become restricted, and you may find it difficult to straighten out your knee. Inflammation and bone friction increase, and you may start to experience stiffness when you out of bed in the morning or after sitting for long periods. These symptoms are often the result of reduced collagen levels in the body, which in turn leads to the degradation of cartilage.

Treatments for knee pain

Medicines like steroids and NSAID are often recommended by doctors for pain relief, and there is no doubt they are all effective. But their side effects are well known. Taking collagen supplements is a safer, natural and extremely effective way to improve one’s overall health and mobility of the joints. Collagen is necessary for the rebuilding and repairing of cartilage and decreases pain symptoms and joint swelling. Puraz takes this approach with their PRO-d product, which is scientifically proven to assist cartilage regeneration. When choosing a collagen supplement, make sure you look for those scientifically tested for its intended benefit.

It might sound contrary, but exercise can really help people coping with knee pain. Very often, knee pain can be improved by correcting underlying muscle imbalances, or building up strength in other areas of the body. A study  in the Osteoarthritis and Cartilage journal described a group of people aged 50 to 79 with osteoarthritis in the knee. Women who had weak quadriceps were found to experience worse knee pain over the 5-year study. Women who had the weakest quadriceps experienced a 28% greater risk that their knee pain would worsen.

A physiotherapist or trained specialist can show you simple exercises to do at home. You might also consider seeing a specialist foot doctor to acquire custom inserts for your shoes. Simply switching to good sturdy shoes with excellent support can go a long way to controlling pain.

Interestingly, smoking has been shown to increase the risk of knee pain. A study published in Annals of the Rheumatic Diseases  found that smoking increased the risk for both cartilage loss and knee pain in men who had developed osteoarthritis in the knee.

Pain and swelling can be reduced with an ice compress but a high-strength topical joint formula is a far more effective solution. You can’t carry ice around in your bag, after all.

Even weight loss can help. Every pound on the body yields five ponds of force on the knee, so just imagine what pressure excessive weight can put on your joints.

Day-to-day living is affected if knee pain is present, but thanks to modern supplements, alongside healthy living, quick relief can be yours.

What is telomere health and how can it help you?

Telomere Health

Telomeres serve to protect chromosomes, but each time a cell divides, the telomeres shorten. When telomeres shorten to critical lengths, the cell dies. Shortened telomeres are linked to ill health and aging.

Telomerase, often referred to as ‘the fountain of youth’, is the key enzyme that repairs telomeres by maintaining telomere length.  That’s important in healthy living, because shortened telomeres directly affect our rate of aging.

What is a telomere?

In simple English, a telomere is a combination of DNA and protein that sits at the end of a chromosome. Like a small cap, it protects the chromosome, which would otherwise deteriorate or fuse with other chromosomes. Telomeres get shorter each time our cells divide, but this is an important part of the aging process. As our cells have a very limited lifespan, cell division is the body’s way of renewing itself and an essential element to our health and vitality.  If cells divided without telomeres, they would lose the ends of their chromosomes, and the important genetic material they contain.

However, each time a cell divides the ends are not completely copied, so over time telomeres get shorter and shorter. When telomeres get too short, the cells can no longer divide and they become senescent or die.

Longer telomeres have been linked to fewer illnesses and longer life, shorter telomeres to disease and mortality. More specifically, shorter telomeres are linked to strokes, cancer, cardiovascular disease, diabetes, dementia, depression, obesity and osteoporosis, among other diseases.

Can we reverse telomere length?

Aging may be inevitable, but the rate of aging is not.  Research shows that telomere shortening can be slowed, stopped or even reversed by maintaining healthy telomerase production in the body. Telomerase rebuilds and replenishes the ends of the chromosomes to keep cells healthy.  If telomerase enzyme levels are high, the telomere length – and our health – is maintained.

Unfortunately, the amount of telomerase in our bodies naturally declines as we get older.  This is where a supplement such as Puraz T5™ is beneficial.

Puraz T5™ contains key ingredients that activate and support our body’s own natural telomerase enzyme production.  It also contains added antioxidants that are essential for protecting against oxidative stress, which is known to accelerate telomere shortening.

It’s just a simple matter of one Puraz T5™ capsule a day for overall health and longevity – and that all-important support for telomeres.

Buy T5 for telomere health and longevity from Puraz Health.

Studies show many fish oils are rancid and lack omega 3. How does Puraz Krill Oil stack up?

Fish oil study

Given recent media reports on problems with fish oil, Puraz has had their Krill Oil product independently tested.

A Nature Journal article reports that a high proportion of retail Fish Oil supplements in New Zealand are of poor quality, containing both high levels of oxidation by-products (which indicate rancidity) and less Omega 3 than stated on the label.

Although Krill Oil supplements were not part of the study, it is understandable that consumers of it may worry.  Nobody wants to consume unhealthy rancid oils, or receive less Omega 3 than they paid for.  For this reason Puraz has taken steps to assure that Puraz Krill Oil is fresh, potent and accurately labelled.

What did the study show in terms of omega 3 and other areas?

• All Fish Oil products available on the New Zealand market were eligible for inclusion. 32 of these were selected.
• Selected products were tested for fatty acid content  and markers of rancidity (peroxide values, anisidine values and total oxidation).
• Only 3 products of those 32 contained the label claimed amount of the Omega 3’s docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA).
• Only 8% of tested products did not exceed internationally recommended levels for indices of oxidation.
• Best-before date, cost, country of origin, and exclusivity were all poor indicators of product quality.

Test results for Puraz Krill Oil capsules

Puraz Krill Oil was analysed by the Cawthron Institute for total Omega 3, EPA, DHA and peroxide values.  The graphs below illustrate how the capsules compare to those featured in the Nature Journal article.

Total Omega 3:

Total Omega 3 was 25% higher than the required amount, with both DHA and EPA levels being at least as high as the label claim.

Puraz Krill Oil was 125% of label claim.

omega 3 graph

Peroxide Value:

The peroxide value of Puraz Krill Oil capules was exceptionally low, almost certainly this is attributable to the high level of astaxanthin, a natural anti-oxidant.  In fact, the level was as low as the laboratory can reliably measure for this rancidity marker. You can’t get better than that.

Puraz Krill Oil level was <0.1 (i.e. lowest they can measure).

omega 3 graph

Get more information or order Puraz Krill Oil today

Author Bio:

Sara Lake
Sara Lake is a Christchurch (New Zealand) based nutritionist, food blogger and MSc student of human nutrition at Massey University.

“Anti-Aging” Is it real?

Anti-aging help

There are many skincare products touting themselves as having anti-aging benefits. This article looks at the science and facts of anti-aging.

From smoothing out those fine lines to firming up sagging skin, anti-aging products make some very enticing promises. And each year consumers spend billions of dollars to find the perfect lotion or potion. But the question is, do anti-aging skincare products actually work? The answer depends on the product.

Defining aging

Aging refers to the biological process of growing older in a deleterious sense (causing harm or damage), which is scientifically referred to as senescence, or the aging of living things. Senescence is associated with many physiological changes, including loss of muscle and bone mass, a decline in memory function and vision, a decline in immune function, a lower metabolic rate, an increase in blood pressure, an increase in inflammation, and so on.

With age, we also see changes in our skin. Our skin becomes thinner and loses elasticity. Fine lines and wrinkles appear, blood vessels become more visible and sagging occurs. Our skin also becomes drier and rougher. Essentially, we lose our “youthful glow”. Which is when people start looking for help.

Anti-aging and skincare

While skincare products cannot restore the skin of our 20-year-old selves, some products can reduce the signs of aging as well as slow the aging process down – and even stimulate the skin’s natural collagen production to produce firmer, younger looking skin.

Collagen is perhaps the most important ingredient to do that. As we age, collagen and elastin fibres degrade and that results in sagging skin and wrinkles.

Unfortunately, the sun, air pollution, cigarette smoke and even household chemicals accelerate the breakdown of collagen. If you add in the fact that our bodies make far less collagen as we get older (a process of senescence), then the signs of aging rapidly set in.

So a beauty regime that protects our skin from harmful UV rays is the first step in the anti-aging process. Avoiding cigarette smoke and chemicals is the second. These small changes make a huge difference to the quality of your skin, and reduce the rapid onset of skin aging.

The next step to anti-aging is to use a product that actually renews your collagen levels. You can’t do this with a cream, as the collagen molecules are too large to penetrate the skin. You need to take a supplement. And you need to make sure you’re taking one with collagen hydrolysate, which is easier for your body to digest, thereby ensuring effectiveness where collagen is used by the body.

Also choose a topical cream that contains antioxidants, including Vitamins C and E, which stop harmful free radicals. Free radicals attack and destroy collagen, among other things. Eating nutritious foods, which contain antioxidants, are also beneficial.

Few people expect a miracle, but these days you can influence your appearance as well as slow down the aging process.

Anti-aging help

Comparing different skin creams

Skin Creams

Do skin creams work? They are not all the same.

With the enormous selection of lotions and creams available, it can be difficult to work out just what’s what, least of all which skincare product is the right one for you.  But if you are looking for healthier, younger looking skin, you need to consider the skin cream you use on a daily basis.

Moisturizer skin creams

On the most basic level, moisturizers are made up of oil and water and bound together by an emulsifier. Their molecules are large, which means they cannot penetrate deep into the skin. But moisturizers can hold moisture in the outermost layer of the skin, preventing and treating dry skin. They also act as a temporary barrier.

Ultimately, the creams available from supermarkets and other stores are designed for a large market and the levels of active ingredients are controlled and their effectiveness limited. That’s not to say they aren’t beneficial, but any improvements to the health of your skin are likely to be minimal. High-end moisturizers on the other hand may include vitamins, anti-oxidants and watering-binding agents, such as hyaluronic acid. These can help improve the look of your skin, making it appear smoother and improving the tone and texture.

Day and night skin creams

There are both day-time and night-time moisturizers. A day moisturizer is often lighter in compounds than a night moisturizer. One reason is that some anti-aging ingredients, such as alpha-hydroxy acids and retinoids, can make the skin more sensitive when exposed to UV rays. Another reason is that your skin does most of its repairing and regenerating while you sleep. Night-creams typically contain powerful ingredients that are designed to penetrate the skin during the course of the night, contributing to the appearance of youthful, smooth skin. Anti-aging components can work as you rest; research suggests that skin may be more receptive to creams at night.

How to find a good night skin cream

To find a good night cream, you need to look at the ingredients. There are three ingredients that are essential for younger looking skin:

1. Hyaluronic acid is something we lose with age but it’s essential for hydrating the skin. All good creams will include hyaluronic acid.

2. We also lose collagen as we age, so we need to replace it if we want to achieve a more youthful appearance. The micro-collagen matrixyl, a powerful peptide that penetrates the skin, incites fibroblast cells to synthesize collagen. It’s crucial for activating the production of collagen, and is the number one ingredient for helping turn back the clock.

3. Argireline is the third essential ingredient. It reduces the depth of expression wrinkles, especially in the forehead and around the eyes. It works on muscle nerve endings, releasing neurotransmitters, which help reduce muscle contraction thereby preventing the formation of lines and wrinkles.

Day serum skin creams

For day use, serums are ideal. Serums are generally oil-based and have smaller molecules that are able to penetrate deep into the skin.

Serums don’t just temporarily improve the skin’s surface, they can help slow down the aging process. An advanced product such as Puraz Anti-Aging Day Serum can rapidly smooth facial skin. It also contains the active molecules argireline and matrixyl, making it the perfect non-invasive alternative for beautiful skin.

A day serum and night cream used alongside your daily moisturizer is the ultimate in healthy skin care. Try Puraz COMPLETE Day Serum & Night Cream – a proven skincare treatment that’s a cut above the rest.

See our skin creams here